I ran into the same problem after updating angular. I did this:

I created igv.d.ts:

declare module '*';

in the same level as app.component.

Then I put createBrowser inside ngAfterViewInit. In retrospect I wonder why it used to work inside ngOnInit, it should be created after the tempalte is rendered....

ngAfterViewInit() {

this.createBrowser()

}

Hope this fixes your problem.